hrp0092p1-325 | Diabetes and Insulin (2) | ESPE2019

Association of CTLA-4 Gene with the Familial Diabetes Mellitus

Saatov Talat , Karimov Khamid , Rakhimova Gulnora , Ibragimov Zafar , Ibragimova Elvira , Ishankgodjaev Tokhir , Alimova Nasiba , Abduvaliev Anvar , Shamansurova Zulaykho

The work was initiated to study role of CTLA4 gene in the onset of familial diabetes mellitus. The samples of peripheral blood taken from children (mean age 12.5 years) of patients with type 1 diabetes mellitus and their blood relatives, such as parents and siblings, and apparently healthy subjects were used in the study. Among the recruits, there were 56.5% of boys and 43.5% of girls. The findings from the genotyping of CTLA4 gene 49A/G polymorphism demonstrated no si...